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Spicy Southern Cheesy Chicken Spaghetti Casserole

A comforting casserole bursting with spicy and cheesy flavors, perfect for busy weeknights and family gatherings.
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Prep Time 15 minutes
Cook Time 30 minutes
Total Time 45 minutes
Servings: 6 servings
Course: Dinner, Main Course
Cuisine: Southern
Calories: 410
Ingredients Method Notes

Ingredients
  

Main Ingredients
  • 1.5 lbs boneless, skinless chicken breasts Fresh or thawed chicken will work best.
  • 8 oz spaghetti Make sure not to overcook as it will absorb moisture in the oven.
  • 2 cups shredded sharp cheddar cheese Freshly shredded cheese is recommended for better meltability.
  • 1 cup fresh bell peppers (chopped) You can swap in your favorite color of bell pepper.
  • 1 can (10.5 oz) cream of chicken soup Can be substituted with homemade or mushroom soup.
Spices
  • 1 tsp paprika
  • 1/2 tsp cayenne pepper Adjust based on your spice preference.
  • 1 tsp garlic powder
Garnish
  • 1/4 cup green onions (sliced) Add for freshness before serving.

Method
 

Preparation
  1. Preheat your oven to 350°F (175°C). Grease a large casserole dish.
  2. Cook the chicken in a large pot over medium heat for about 6-7 minutes per side until golden and cooked through. Let it cool slightly before shredding.
  3. In a separate pot, boil salted water and cook spaghetti until al dente, about 8-10 minutes. Drain and set aside.
Mix and Bake
  1. In a large bowl, mix shredded chicken, cooked spaghetti, cream of chicken soup, chopped bell peppers, paprika, cayenne pepper, garlic powder, and half of the cheddar cheese until evenly combined.
  2. Pour the mixture into the greased casserole dish and spread it out. Top with the remaining cheddar cheese.
  3. Bake for 25-30 minutes, or until bubbly and cheese is golden brown.
Serving
  1. Let the casserole rest for about 5 minutes before serving. Garnish with sliced green onions.

Notes

You can prepare this casserole a day in advance and refrigerate until ready to bake. For long-term storage, cover well and freeze for up to three months.